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We establish that a complete, natural hormonal environment (hemolymph) increases the likelihood of a neuropeptide activating the gastric mill (chewing) rhythm in the crab stomatogastric ganglion (STG). The similar action of a higher neuropeptide concentration in saline, its comparable desensitizing effect to that of neuropeptide plus hemolymph on subsequent neuropeptide applications, and the absence of that neuropeptide in hemolymph suggest one or more distinct hormones act to enhance the effectiveness of the applied peptide.more » « lessFree, publicly-accessible full text available August 1, 2026
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